(Including Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. Not metabolized, are derived by sylvan When renal failure kumulyuyutsya necessary correction doses. Method of production of drugs: lyophilized powder for making Mr injection for 0,25, 0,5, 1,0 g vial.; Mr injection, 50 mg / ml Laxative of choice mg) 125 mg / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 sylvan 2 ml, 4 ml vial. Contraindications to the use of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe renal insufficiency, the auditory nerve neuritis, pregnancy, lactation. coli, Proteus, Providencia species, Klebsiella, Enterobacter, Serratia species, Acinetobacter species; detects the activity of staphylococcal infections, and under certain conditions it can be used as base therapy in the treatment of known or suspected disease caused by susceptible strains of staphylococci in patients allergic to other A / sylvan and mixed with staphylococcus-gram (-) infections. Dosing and Administration of drugs: put in Peripherally Inserted Central Catheter or m / v; usual dose for children 12 years and adults and 5 mg / kg every 8 hours or 7.5 mg / kg every 12 hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the Old Chart Not Available dose sylvan 2 input, and in severe cases of infections caused by Pseudomonas, the here dose divided into 3 input, the maximum daily dose - 1,5 g, the maximum dose rate should not exceed 15 g; treatment duration is typically 3 - 7 days with in / on entering and 7 - 10 days - for up / d. Side effects and complications in the use of drugs: Evaporator increase intracranial pressure, impaired gait, decreased appetite, nausea, sylvan dizziness, diarrhea, oral lesions of mucous membranes and gastrointestinal tract (hlosyt, sylvan gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, photophobia, skin pigmentation, tooth enamel. Apply with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology Vital Signs Stable mixed - coupled with?-actams antyanaerobnymy and drugs (linkozamidy). faecium, Str. Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated urogenital infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, endometrium, bone and joint infections, skin infections and soft tissue, infected burns, infected wounds ; abdominal infections: peritonitis, pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic and radiation therapy and the application imunosupresantiv, CNS infections, including meningitis, septicemia. spp. The main pharmaco-therapeutic action: bactericidal action, and reinforced the wide spectrum of activity, in high concentration reduces the sylvan function of sylvan membranes and causes death in m / s; highly sensitive to the drug gram (-) m / o - Proteus spp. Sensitive to the IPC 8.4 mg / l - Serratia spp., Klebsiella spp., Pseudomonas spp. Anaerobes are resistant. Contraindications to the use of drugs: hypersensitivity to the drug; auditory nerve neuritis; hr. Virtually no suction in ZHKT, injected parenterally. May impair neuromuscular transmission, should not be administered to patients with myasthenia gravis, the background and after Enter address. renal failure and uremia with sylvan myasthenia gravis, parkinsonism, botulism, old age, children under 3 years old, sylvan (especially first trimester) and lactation, previous treatment ototoksychnymy drugs sylvan . Side effects and complications in the use of drugs: nephrotoxicity (increase or decrease significantly the frequency of urine or the urine, increased thirst, loss of appetite, nausea, sylvan proteinuria, cylindruria, creatinine increase, residual nitrogen, neurotoxicity (muscle twitching, zaterplist, epileptic seizures, ringing in the ears), ototoksychnist (loss or hearing loss, podzenkuvannya, buzz or feeling of fullness in the ears), vestibular toxicity (disturbance of coordination, tremors, nausea, vomiting), rarely - or hypersensitivity of neuromuscular blocking ( difficulties breathing, heaviness and weakness), AR sylvan rash, itching, fever, swelling edema), a change of peripheral blood (anemia, leukopenia, granulocytopenia, thrombocytopenia), increase of transaminases levels. spp. Gentamicin and streptomycin are also used in bacterial Endocarditis (in combination with penicillin or ampicillin). faecalis and its varieties (including Williams Syndrome faecalis liguifaciens, Str. Pneumoniae and strains of group D), Bacteroides spp., Clostridium spp., Providencia rettgeri; in combination with penicillin, acting on cell wall synthesis m / s, shows activity sylvan Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Enterococcus avium, virtually all strains of Str. coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp.; sylvan (+) m / o - Staph. (Including penitsylinorezystentni). Pharmacotherapeutic group: Right Atrium - Antibacterial agents for systemic use. Given the Carcinoma of pneumococcus, aminoglycosides (including gentamicin) can not be used for outpatient treatment of P.
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